20 Southern Casserole Recipes We Learned from Grandma (2024)

Home Recipes Casseroles

Southern grandmas seem to know the best comforting dishes to make and these Southern casserole recipes are definitely some of their best!

Chicken Potpie Casserole

I always have leftover chicken broth on hand and use it for many things, including this comforting family favorite. You can bake your own biscuits as I do or buy them at the store. I like to bake extra biscuits to eat with butter and jam. —Liliane Jahnke, Cypress, Texas

Vegetable Beef Casserole

This easy one-dish recipe has been a family favorite ever since my husband's aunt handed it down to me decades ago. Try using whatever vegetables you have on hand. A simple salad goes nicely with this entree. —Evangeline Rew, Manassas, Virginia

Easy Cheesy Loaded Grits

A tasty bowl of grits inspired me to develop my own recipe with sausage, green chiles and cheeses. It just might be better than the original. —Joan Hallford, North Richland Hills, Texas

Coconut-Bourbon Sweet Potatoes

What is it about sweet potatoes that unnerve some people? For those who firmly state they hate a yam because of the color or texture, the rich addition of coconut, bourbon and spices might just win them over. —Rebecca Anderson, Driftwood, Texas

Hot Brown Turkey Casserole

If you've ever tried the Hot Brown Sandwich at the Brown Hotel in Louisville, Kentucky, you'll love this version. It can be assembled ahead and refrigerated; just adjust baking time accordingly if cold. —Diane Halferty, Corpus Christi, Texas

Chicken and Rice Casserole

Everyone loves this dish—I consider it the best chicken and rice casserole recipe because it's a tasty combination of hearty and crunchy ingredients mixed in a creamy sauce. It's a time-tested classic. —Myrtle Matthews, Marietta, Georgia

Loaded Red Potato Casserole

This potato casserole has the same flavor of the potato skins you can order as a restaurant appetizer. It's an ideal dish for tailgating and potlucks. —Charlane Gathy, Lexington, Kentucky

Cranberry-Apple French Toast

My husband's breakfast club at work raves about this make-ahead French toast. Pop it in the oven in the morning to get your day off to a sweet, bubbly start. —Mara Faulkner, Martinsburg, West Virginia

Loaded Twice-Baked Potato Casserole

My husband is a meat and potatoes guy, so I try new combinations for variety. In this dish, twice-baked potatoes and potato skins make a scrumptious casserole. —Cyndy Gerken, Naples, Florida

Blend of the Bayou

My sister-in-law shared this recipe with me when I first moved here. It's been handed down in my husband's family for generations. It's quick to prepare, nutritious and flavorful. I've passed it on to my children too.—Ruby Williams, Bogalusa, Louisiana

Breakfast Burrito Casserole

A friend gave me this burrito casserole recipe and I modified it to fit our family. It's perfect for a brunch, because you can prep it the night before and bake it the next morning. —Krista Yoder, Due West, South Carolina

In the South, everyone loves three things: bacon, cheese and grits! After playing around with this recipe, I took it to my first family party as a newlywed, and it was a huge hit. This recipe has become a family tradition that I'm sure will be passed down for generations. —Melissa Rogers, Tuscaloosa, Alabama

New Orleans-Style Scalloped Corn

This colorful casserole is very popular among family gatherings in many New Orleans homes. I started making it years ago, and now my sons include it in their menus.—Mrs. Priscilla Gilbert, Indian Harbour Beach, Florida

Cornbread Chicken Bake

To make the most of leftover cornbread, try this hearty main dish casserole. It's moist, delicious and good on any occasion. —Madge Britton, Afton, Tennessee

Calico Squash Casserole

I love to try out different recipes for the squash I grow in my garden. It's fun to bring this beautiful casserole to potlucks because I know it'll go fast. Even the little ones like it. —Lucille Terry, Frankfort, Kentucky

Chili Beef Cornbread Casserole

This recipe is my potluck standby. And when I hear that someone may need a comforting home-cooked meal, I bring them this casserole. —Lorraine Espenhain, Corpus Christi, Texas

Chiles Rellenos Breakfast Bake

My family loves anything with a Southwestern flavor, so I turned classic chiles rellenos into a breakfast casserole. They became fans in an instant. —Joan Hallford, North Richland Hills, Texas

Pepper Jack Hash Brown Casserole

I found myself in need of an impromptu potato dish, but I had no potatoes. Frozen hash browns and the plethora of cheeses I had in the freezer offered me the solution to my side-dish dilemma. —Cynthia Gerken, Naples, Florida

Lisa is a formerTaste of Home editor and passionate baker. During her tenure, she poured her love of all things sweet (and sometimes savory) into Bakeable, Taste of Home's baking club. Lisa also dedicated her career here to finding and testing the best ingredients, kitchen gear and home products for our Test Kitchen-Preferred program. At home, you'll find her working on embroidery and other crafts.